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Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina
There is much debate on the adeno-associated virus (AAV) serotype that best targets specific retinal cell types and the route of surgical delivery—intravitreal or subretinal. This study compared three of the most efficacious AAV vectors known to date in a mouse model of retinal degeneration (rd1 mou...
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| Udgivet i: | Gene Ther |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5746594/ https://ncbi.nlm.nih.gov/pubmed/28872643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2017.85 |
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