Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina

There is much debate on the adeno-associated virus (AAV) serotype that best targets specific retinal cell types and the route of surgical delivery—intravitreal or subretinal. This study compared three of the most efficacious AAV vectors known to date in a mouse model of retinal degeneration (rd1 mou...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Gene Ther
Auteurs principaux: Hickey, D G, Edwards, T L, Barnard, A R, Singh, M S, de Silva, S R, McClements, M E, Flannery, J G, Hankins, M W, MacLaren, R E
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746594/
https://ncbi.nlm.nih.gov/pubmed/28872643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2017.85
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires