DNase-capture reveals differential transcription factor binding modalities

We describe DNase-capture, an assay that increases the analytical resolution of DNase-seq by focusing its sequencing phase on selected genomic regions. We introduce a new method to compensate for capture bias called BaseNormal that allows for accurate recovery of transcription factor protection prof...

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Udgivet i:PLoS One
Main Authors: Kang, Daniel, Sherwood, Richard, Barkal, Amira, Hashimoto, Tatsunori, Engstrom, Logan, Gifford, David
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746236/
https://ncbi.nlm.nih.gov/pubmed/29284001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187046
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