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Autophagy flux inhibition, G2/M cell cycle arrest and apoptosis induction by ubenimex in glioma cell lines

This study aimed to investigate whether ubenimex could work as an anti-tumor drug alone in glioma cells and figure out the underlying potential mechanisms. Ubenimex is widely used as an adjunct therapy in multiple solid cancers. However, it is rarely used to treat glioblastoma. The function of ubeni...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Han, Liping, Zhang, Yongfei, Liu, Shuai, Zhao, Qingwei, Liang, Xianhong, Ma, Zhiguo, Gupta, Prakash K., Zhao, Miaoqing, Wang, Aihua
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746103/
https://ncbi.nlm.nih.gov/pubmed/29296201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22594
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