Artesunate Impairs Growth in Cisplatin-Resistant Bladder Cancer Cells by Cell Cycle Arrest, Apoptosis and Autophagy Induction

Cisplatin, which induces DNA damage, is standard chemotherapy for advanced bladder cancer (BCa). However, efficacy is limited due to resistance development. Since artesunate (ART), a derivative of artemisinin originating from Traditional Chinese Medicine, has been shown to exhibit anti-tumor activit...

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Bibliographic Details
Published in:Cells
Main Authors: Zhao, Fuguang, Vakhrusheva, Olesya, Markowitsch, Sascha D., Slade, Kimberly S., Tsaur, Igor, Cinatl, Jindrich, Michaelis, Martin, Efferth, Thomas, Haferkamp, Axel, Juengel, Eva
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763932/
https://ncbi.nlm.nih.gov/pubmed/33316936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9122643
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