Artesunate Impairs Growth in Cisplatin-Resistant Bladder Cancer Cells by Cell Cycle Arrest, Apoptosis and Autophagy Induction

Cisplatin, which induces DNA damage, is standard chemotherapy for advanced bladder cancer (BCa). However, efficacy is limited due to resistance development. Since artesunate (ART), a derivative of artemisinin originating from Traditional Chinese Medicine, has been shown to exhibit anti-tumor activit...

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Publicat a:Cells
Autors principals: Zhao, Fuguang, Vakhrusheva, Olesya, Markowitsch, Sascha D., Slade, Kimberly S., Tsaur, Igor, Cinatl, Jindrich, Michaelis, Martin, Efferth, Thomas, Haferkamp, Axel, Juengel, Eva
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763932/
https://ncbi.nlm.nih.gov/pubmed/33316936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9122643
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