Cisplatin resistance in non-small cell lung cancer cells is associated with an abrogation of cisplatin-induced G(2)/M cell cycle arrest

The efficacy of cisplatin-based chemotherapy in cancer is limited by the occurrence of innate and acquired drug resistance. In order to better understand the mechanisms underlying acquired cisplatin resistance, we have compared the adenocarcinoma-derived non-small cell lung cancer (NSCLC) cell line...

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Udgivet i:PLoS One
Main Authors: Sarin, Navin, Engel, Florian, Kalayda, Ganna V., Mannewitz, Mareike, Cinatl, Jindrich, Rothweiler, Florian, Michaelis, Martin, Saafan, Hisham, Ritter, Christoph A., Jaehde, Ulrich, Frötschl, Roland
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528889/
https://ncbi.nlm.nih.gov/pubmed/28746345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181081
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