Cisplatin resistance in non-small cell lung cancer cells is associated with an abrogation of cisplatin-induced G(2)/M cell cycle arrest

The efficacy of cisplatin-based chemotherapy in cancer is limited by the occurrence of innate and acquired drug resistance. In order to better understand the mechanisms underlying acquired cisplatin resistance, we have compared the adenocarcinoma-derived non-small cell lung cancer (NSCLC) cell line...

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Publicat a:PLoS One
Autors principals: Sarin, Navin, Engel, Florian, Kalayda, Ganna V., Mannewitz, Mareike, Cinatl, Jindrich, Rothweiler, Florian, Michaelis, Martin, Saafan, Hisham, Ritter, Christoph A., Jaehde, Ulrich, Frötschl, Roland
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528889/
https://ncbi.nlm.nih.gov/pubmed/28746345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181081
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