Autophagy flux inhibition, G2/M cell cycle arrest and apoptosis induction by ubenimex in glioma cell lines

This study aimed to investigate whether ubenimex could work as an anti-tumor drug alone in glioma cells and figure out the underlying potential mechanisms. Ubenimex is widely used as an adjunct therapy in multiple solid cancers. However, it is rarely used to treat glioblastoma. The function of ubeni...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Han, Liping, Zhang, Yongfei, Liu, Shuai, Zhao, Qingwei, Liang, Xianhong, Ma, Zhiguo, Gupta, Prakash K., Zhao, Miaoqing, Wang, Aihua
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746103/
https://ncbi.nlm.nih.gov/pubmed/29296201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22594
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