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EZH2 modulates the DNA methylome and controls T cell adhesion through junctional adhesion molecule-A in lupus patients
OBJECTIVE: EZH2 is an epigenetic regulator that mediates H3K27 trimethylation and modulates DNA methylation. The aim of this study is to characterize the role of EZH2 in CD4+ T cells upon lupus pathogenesis. METHODS: EZH2 expression levels were determined in CD4+ T cells isolated from lupus patients...
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| Pubblicato in: | Arthritis Rheumatol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5745285/ https://ncbi.nlm.nih.gov/pubmed/28973837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40338 |
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