Llwytho...

EZH2 modulates the DNA methylome and controls T cell adhesion through junctional adhesion molecule-A in lupus patients

OBJECTIVE: EZH2 is an epigenetic regulator that mediates H3K27 trimethylation and modulates DNA methylation. The aim of this study is to characterize the role of EZH2 in CD4+ T cells upon lupus pathogenesis. METHODS: EZH2 expression levels were determined in CD4+ T cells isolated from lupus patients...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Arthritis Rheumatol
Prif Awduron: Tsou, Pei-Suen, Coit, Patrick, Kilian, Nathan C., Sawalha, Amr H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745285/
https://ncbi.nlm.nih.gov/pubmed/28973837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40338
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