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Sulfamate Esters Guide Selective Radical-Mediated Chlorination of Aliphatic C–H Bonds

Masked alcohols are particularly appealing as directing groups because of the ubiquity of hydroxyl groups in organic small molecules. Herein, we disclose a general strategy for aliphatic γ-C(sp(3))–H functionalization guided by a masked alcohol. Specifically, we determine that sulfamate ester-derive...

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Publicado en:Angew Chem Int Ed Engl
Main Authors: Short, Melanie A., Blackburn, J. Miles, Roizen, Jennifer L.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745255/
https://ncbi.nlm.nih.gov/pubmed/29096044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201710322
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