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Synthesis of N-substituted sulfamate esters from sulfamic acid salts by activation with triphenylphosphine ditriflate

A general approach to access sulfamate esters through preparation of sulfamic acid salts, subsequent activation with triphenylphosphonium ditriflate, and nucleophilic trapping is disclosed. The method proceeds in modest to excellent yields to incorporate nucleophiles derived from aliphatic alcohols...

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發表在:Org Lett
Main Authors: Blackburn, J. Miles, Short, Melanie A., Castanheiro, Thomas, Ayer, Suraj K., Muellers, Tobias D., Roizen, Jennifer L.
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716482/
https://ncbi.nlm.nih.gov/pubmed/29048913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b03059
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