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Modifying Positional Selectivity in C–H Functionalization Reactions with Nitrogen-Centered Radicals: Generalizable Approaches to 1,6-Hydrogen-Atom Transfer Processes

Nitrogen-centered radicals are powerful reaction intermediates owing in part to their ability to guide position-selective C(sp(3))–H functionalization reactions. Typically, these reactive species dictate the site of functionalization by preferentially engaging in 1,5-hydrogen-atom transfer (1,5-HAT)...

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Detalhes bibliográficos
Publicado no:Synlett
Main Authors: Short, Melanie A., Blackburn, J. Miles, Roizen, Jennifer L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115226/
https://ncbi.nlm.nih.gov/pubmed/33986583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0039-1691501
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