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Virtual Cell Based Assay simulations of intra-mitochondrial concentrations in hepatocytes and cardiomyocytes

In order to replace the use of animals in toxicity testing, there is a need to predict human in vivo toxic doses from concentrations that cause adverse effects in in vitro test systems. The virtual cell based assay (VCBA) has been developed to simulate intracellular concentrations as a function of t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Toxicol In Vitro
मुख्य लेखकों: Worth, Andrew P., Louisse, Jochem, Macko, Peter, Sala Benito, J.V., Paini, Alicia
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Pergamon Press 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745147/
https://ncbi.nlm.nih.gov/pubmed/28911986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2017.09.009
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