The class I scavenger receptor CD163 promotes internalization of ADAMTS13 by macrophages

Internalization of ADAMTS13 by macrophages may contribute to its clearance from the circulation. Here we investigated endocytic mechanisms that contribute to the uptake of ADAMTS13 by macrophages. Human monocyte-derived macrophages were used to monitor the uptake of fluorescently labeled recombinant...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Verbij, Fabian C., Sorvillo, Nicoletta, Kaijen, Paul H. P., Hrdinova, Johana, Peyron, Ivan, Fijnheer, Rob, ten Brinke, Anja, Meijer, Alexander B., van Alphen, Floris P. J., van den Berg, Timo K., Graversen, Jonas J. H., Moestrup, Soren K., Voorberg, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744037/
https://ncbi.nlm.nih.gov/pubmed/29296945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2016001321
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