von Willebrand factor binds to the surface of dendritic cells and modulates peptide presentation of factor VIII

It has been proposed that von Willebrand factor might affect factor VIII immunogenicity by reducing factor VIII uptake by antigen presenting cells. Here we investigate the interaction of recombinant von Willebrand factor with immature monocyte-derived dendritic cells using flow cytometry and confoca...

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Publicado no:Haematologica
Main Authors: Sorvillo, Nicoletta, Hartholt, Robin B., Bloem, Esther, Sedek, Magdalena, Brinke, Anja ten, van der Zwaan, Carmen, van Alphen, Floris P., Meijer, Alexander B., Voorberg, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815722/
https://ncbi.nlm.nih.gov/pubmed/26635035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.137067
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