von Willebrand factor binds to the surface of dendritic cells and modulates peptide presentation of factor VIII

It has been proposed that von Willebrand factor might affect factor VIII immunogenicity by reducing factor VIII uptake by antigen presenting cells. Here we investigate the interaction of recombinant von Willebrand factor with immature monocyte-derived dendritic cells using flow cytometry and confoca...

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Bibliografski detalji
Izdano u:Haematologica
Glavni autori: Sorvillo, Nicoletta, Hartholt, Robin B., Bloem, Esther, Sedek, Magdalena, Brinke, Anja ten, van der Zwaan, Carmen, van Alphen, Floris P., Meijer, Alexander B., Voorberg, Jan
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2016
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Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815722/
https://ncbi.nlm.nih.gov/pubmed/26635035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.137067
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