Mass spectrometry-assisted identification of ADAMTS13-derived peptides presented on HLA-DR and HLA-DQ

Formation of microthrombi is a hallmark of acquired thrombotic thrombocytopenic purpura. These microthrombi originate from insufficient processing of ultra large von Willebrand factor multimers by ADAMTS13 due to the development of anti-ADAMTS13 autoantibodies. Several studies have identified the ma...

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Udgivet i:Haematologica
Main Authors: Hrdinová, Johana, Verbij, Fabian C., Kaijen, Paul H.P., Hartholt, Robin B., van Alphen, Floris, Lardy, Neubury, ten Brinke, Anja, Vanhoorelbeke, Karen, Hindocha, Pooja J., De Groot, Anne S., Meijer, Alexander B., Voorberg, Jan, Peyron, Ivan
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058777/
https://ncbi.nlm.nih.gov/pubmed/29567779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.179119
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