LARG GEF and ARHGAP18 Orchestrate RhoA Activity to Control Mesenchymal Stem Cell Lineage

The quantity and quality of bone depends on osteoblastic differentiation of mesenchymal stem cells (MSCs), where adipogenic commitment depletes the available pool for osteogenesis. Cell architecture influences lineage decisions, where interfering with cytoskeletal structure promotes adipogenesis. Me...

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Enregistré dans:
Détails bibliographiques
Publié dans:Bone
Auteurs principaux: Thompson, William R., Yen, Sherwin S., Uzer, Gunes, Xie, Zhihui, Sen, Buer, Styner, Maya, Burridge, Keith, Rubin, Janet
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743610/
https://ncbi.nlm.nih.gov/pubmed/29208526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2017.12.001
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