Cell Mechanosensitivity to Extremely Low Magnitude Signals is Enabled by a LINCed Nucleus

A cell’s ability to recognize and adapt to the physical environment is central to its survival and function, but how mechanical cues are perceived and transduced into intracellular signals remains unclear. In mesenchymal stem cells (MSC), high magnitude substrate strain (HMS, ≥2%) effectively suppre...

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Bibliografski detalji
Izdano u:Stem Cells
Glavni autori: Uzer, Gunes, Thompson, William R., Sen, Buer, Xie, Zhihui, Yen, Sherwin S., Miller, Sean, Bas, Guniz, Styner, Maya, Rubin, Clinton T., Judex, Stefan, Burridge, Keith, Rubin, Janet
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458857/
https://ncbi.nlm.nih.gov/pubmed/25787126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2004
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