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Cell Mechanosensitivity to Extremely Low Magnitude Signals is Enabled by a LINCed Nucleus

A cell’s ability to recognize and adapt to the physical environment is central to its survival and function, but how mechanical cues are perceived and transduced into intracellular signals remains unclear. In mesenchymal stem cells (MSC), high magnitude substrate strain (HMS, ≥2%) effectively suppre...

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書目詳細資料
發表在:Stem Cells
Main Authors: Uzer, Gunes, Thompson, William R., Sen, Buer, Xie, Zhihui, Yen, Sherwin S., Miller, Sean, Bas, Guniz, Styner, Maya, Rubin, Clinton T., Judex, Stefan, Burridge, Keith, Rubin, Janet
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458857/
https://ncbi.nlm.nih.gov/pubmed/25787126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2004
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