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Cell Mechanosensitivity to Extremely Low Magnitude Signals is Enabled by a LINCed Nucleus

A cell’s ability to recognize and adapt to the physical environment is central to its survival and function, but how mechanical cues are perceived and transduced into intracellular signals remains unclear. In mesenchymal stem cells (MSC), high magnitude substrate strain (HMS, ≥2%) effectively suppre...

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Podrobná bibliografie
Vydáno v:Stem Cells
Hlavní autoři: Uzer, Gunes, Thompson, William R., Sen, Buer, Xie, Zhihui, Yen, Sherwin S., Miller, Sean, Bas, Guniz, Styner, Maya, Rubin, Clinton T., Judex, Stefan, Burridge, Keith, Rubin, Janet
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458857/
https://ncbi.nlm.nih.gov/pubmed/25787126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2004
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