Synthetic Three-Component HIV-1 V3 Glycopeptide Immunogens Induce Glycan-Dependent Antibody Responses

Eliciting broadly neutralizing antibody (bNAb) responses against HIV-1 is a major goal for a prophylactic HIV-1 vaccine. One approach is to design immunogens based on known broadly neutralizing epitopes. Here we report the design and synthesis of an HIV-1 glycopeptide immunogen derived from the V3 d...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Cell Chem Biol
Autores principales: Cai, Hui, Orwenyo, Jared, Giddens, John P., Yang, Qiang, Zhang, Roushu, LaBranche, Celia C., Montefiori, David C., Wang, Lai-Xi
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741509/
https://ncbi.nlm.nih.gov/pubmed/29107699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2017.09.005
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares