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Quantitative analysis of the rates for repeat-mediated genome instability in a yeast experimental system
Instability of repetitive DNA sequences causes numerous hereditary disorders in humans, the majority of which are associated with trinucleotide repeat expansions. Here we describe a unique system to study instability of triplet repeats in a yeast experimental settings. Using fluctuation assay and th...
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| Publicado en: | Methods Mol Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5741187/ https://ncbi.nlm.nih.gov/pubmed/29043640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7306-4_29 |
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