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Coupling transcriptional state to large-scale repeat expansions in yeast

Expansions of simple DNA repeats cause numerous hereditary disorders in humans. Replication, repair and transcription are implicated in the expansion process, but their relative contributions are yet to be distinguished. To separate the role of replication and transcription in the expansion of Fried...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Shah, Kartik A., McGinty, Ryan J., Egorova, Vera I., Mirkin, Sergei M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268310/
https://ncbi.nlm.nih.gov/pubmed/25464841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.10.048
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