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Quantitative analysis of the rates for repeat-mediated genome instability in a yeast experimental system
Instability of repetitive DNA sequences causes numerous hereditary disorders in humans, the majority of which are associated with trinucleotide repeat expansions. Here we describe a unique system to study instability of triplet repeats in a yeast experimental settings. Using fluctuation assay and th...
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| Publicat a: | Methods Mol Biol |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5741187/ https://ncbi.nlm.nih.gov/pubmed/29043640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7306-4_29 |
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