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K(V)7 Channel Pharmacological Activation by the Novel Activator ML213: Role for Heteromeric K(V)7.4/K(V)7.5 Channels in Guinea Pig Detrusor Smooth Muscle Function

Voltage-gated K(V)7 channels (K(V)7.1 to K(V)7.5) are important regulators of the cell membrane potential in detrusor smooth muscle (DSM) of the urinary bladder. This study sought to further the current knowledge of K(V)7 channel function at the molecular, cellular, and tissue levels in combination...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Provence, Aaron, Angoli, Damiano, Petkov, Georgi V.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741046/
https://ncbi.nlm.nih.gov/pubmed/29084816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.243162
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