Differential Activation of Vascular Smooth Muscle Kv7.4, Kv7.5, and Kv7.4/7.5 Channels by ML213 and ICA-069673

Recent research suggests that smooth muscle cells express Kv7.4 and Kv7.5 voltage-activated potassium channels, which contribute to maintenance of their resting membrane voltage. New pharmacologic activators of Kv7 channels, ML213 (N-mesitybicyclo[2.2.1]heptane-2-carboxamide) and ICA-069673 N-(6-chl...

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Hlavní autoři: Brueggemann, Lyubov I., Haick, Jennifer M., Cribbs, Leanne L., Byron, Kenneth L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2014
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152906/
https://ncbi.nlm.nih.gov/pubmed/24944189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.093799
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