Roscovitine strongly enhances the effect of olaparib on radiosensitivity for HPV neg. but not for HPV pos. HNSCC cell lines

At present, advanced stage human Papillomavirus (HPV) negative and positive head and neck squamous cell carcinoma (HNSCC) are treated by intense multimodal therapy that includes radiochemotherapy, which are associated with relevant side effects. Patients with HPV positive tumors possess a far better...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Ziemann, Frank, Seltzsam, Steve, Dreffke, Kristin, Preising, Stefanie, Arenz, Andrea, Subtil, Florentine S.B., Rieckmann, Thorsten, Engenhart-Cabillic, Rita, Dikomey, Ekkehard, Wittig, Andrea
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739629/
https://ncbi.nlm.nih.gov/pubmed/29285242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22005
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