Roscovitine strongly enhances the effect of olaparib on radiosensitivity for HPV neg. but not for HPV pos. HNSCC cell lines

At present, advanced stage human Papillomavirus (HPV) negative and positive head and neck squamous cell carcinoma (HNSCC) are treated by intense multimodal therapy that includes radiochemotherapy, which are associated with relevant side effects. Patients with HPV positive tumors possess a far better...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ziemann, Frank, Seltzsam, Steve, Dreffke, Kristin, Preising, Stefanie, Arenz, Andrea, Subtil, Florentine S.B., Rieckmann, Thorsten, Engenhart-Cabillic, Rita, Dikomey, Ekkehard, Wittig, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739629/
https://ncbi.nlm.nih.gov/pubmed/29285242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22005
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