In HPV-Positive HNSCC Cells, Functional Restoration of the p53/p21 Pathway by Proteasome Inhibitor Bortezomib Does Not Affect Radio- or Chemosensitivity()()

Human papillomavirus (HPV) associated squamous cell carcinomas of the head and neck region (HPV+ HNSCCs) harbor diverging biological features as compared to classical noxa-induced (HPV−) HNSCC. One striking difference between subtypes is that the tumor suppressor gene TP53 is usually not mutated in...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Seltzsam, Steve, Ziemann, Frank, Dreffke, Kristin, Preising, Stefanie, Arenz, Andrea, Schötz, Ulrike, Engenhart-Cabillic, Rita, Dikomey, Ekkehard, Wittig, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2018
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370941/
https://ncbi.nlm.nih.gov/pubmed/30554133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.11.013
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