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Roscovitine strongly enhances the effect of olaparib on radiosensitivity for HPV neg. but not for HPV pos. HNSCC cell lines

At present, advanced stage human Papillomavirus (HPV) negative and positive head and neck squamous cell carcinoma (HNSCC) are treated by intense multimodal therapy that includes radiochemotherapy, which are associated with relevant side effects. Patients with HPV positive tumors possess a far better...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Ziemann, Frank, Seltzsam, Steve, Dreffke, Kristin, Preising, Stefanie, Arenz, Andrea, Subtil, Florentine S.B., Rieckmann, Thorsten, Engenhart-Cabillic, Rita, Dikomey, Ekkehard, Wittig, Andrea
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739629/
https://ncbi.nlm.nih.gov/pubmed/29285242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22005
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