Novel GM-CSF signals via IFN-γR/IRF-1 and AKT/mTOR license monocytes for suppressor function

Granulocyte-macrophage colony-stimulating factor (GM-CSF) controls proliferation and survival of myeloid cells including monocytes. Here, we describe a time-dependent licensing process driven by GM-CSF in murine Ly6C(high) and human CD14(+) monocytes that disables their inflammatory functions and pr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood Adv
Egile Nagusiak: Ribechini, Eliana, Hutchinson, James A., Hergovits, Sabine, Heuer, Marion, Lucas, Jörg, Schleicher, Ulrike, Jordán Garrote, Ana-Laura, Potter, Sarah J., Riquelme, Paloma, Brackmann, Heike, Müller, Nora, Raifer, Hartmann, Berberich, Ingolf, Huber, Magdalena, Beilhack, Andreas, Lohoff, Michael, Bogdan, Christian, Eyrich, Matthias, Hermanns, Heike M., Geissler, Edward K., Lutz, Manfred B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2017
Gaiak:
Immunobiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737598/
https://ncbi.nlm.nih.gov/pubmed/29296736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017006858
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak