Role of GM-CSF signaling in cell-based tumor immunization

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a potent adjuvant in cancer vaccination; however, the specific role of endogenous GM-CSF remains unknown. We performed cell-based vaccination in 2 tumor models. First, we vaccinated C57BL/6 mice lacking either GM-CSF, IL-5, or beta-common...

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Detalhes bibliográficos
Main Authors: Zarei, Shohreh, Schwenter, Frank, Luy, Patricia, Aurrand-Lions, Michel, Morel, Philippe, Kopf, Manfred, Dranoff, Glenn, Mach, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943756/
https://ncbi.nlm.nih.gov/pubmed/19282460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-06-161075
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