Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient mice.

Mutation of the granulocyte-macrophage colony-stimulating factor (GM-CSF) gene by homologous recombination caused alveolar proteinosis in mice. To further discern the role of GM-CSF in surfactant homeostasis, the synthesis of GM-CSF was directed to the respiratory epithelium of GM-CSF-hull mutant mi...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Huffman, J A, Hull, W M, Dranoff, G, Mulligan, R C, Whitsett, J A
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1996
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Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507100/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8609219/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118461
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