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Thematic Review Series: Lipid Transfer Proteins ABCG5 and ABCG8: more than a defense against xenosterols

The elucidation of the molecular basis of the rare disease, sitosterolemia, has revolutionized our mechanistic understanding of how dietary sterols are excreted and how cholesterol is eliminated from the body. Two proteins, ABCG5 and ABCG8, encoded by the sitosterolemia locus, work as obligate dimer...

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Autori principali: Shailendra B. Patel, Gregory A. Graf, Ryan E. Temel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018-01-01
Serie:Journal of Lipid Research
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Accesso online:http://www.sciencedirect.com/science/article/pii/S0022227520330716
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