Detection of wild-type EGFR amplification and EGFRvIII mutation in CSF-derived extracellular vesicles of glioblastoma patients

BACKGROUND: RNAs within extracellular vesicles (EVs) have potential as diagnostic biomarkers for patients with cancer and are identified in a variety of biofluids. Glioblastomas (GBMs) release EVs containing RNA into cerebrospinal fluid (CSF). Here we describe a multi-institutional study of RNA extr...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Figueroa, Javier M, Skog, Johan, Akers, Johnny, Li, Hongying, Komotar, Ricardo, Jensen, Randy, Ringel, Florian, Yang, Isaac, Kalkanis, Steven, Thompson, Reid, LoGuidice, Lori, Berghoff, Emily, Parsa, Andrew, Liau, Linda, Curry, William, Cahill, Daniel, Bettegowda, Chetan, Lang, Frederick F, Chiocca, E Antonio, Henson, John, Kim, Ryan, Breakefield, Xandra, Chen, Clark, Messer, Karen, Hochberg, Fred, Carter, Bob S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737576/
https://ncbi.nlm.nih.gov/pubmed/28453784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox085
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