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Pharmacokinetic interactions and dosing rationale for antiepileptic drugs in adults and children

AIMS: Population pharmacokinetic modelling has been widely used across many therapeutic areas to identify sources of variability, which are incorporated into models as covariate factors. Despite numerous publications on pharmacokinetic drug–drug interactions (DDIs) between antiepileptic drugs (AEDs)...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: van Dijkman, Sven C., Rauwé, Willem M., Danhof, Meindert, Della Pasqua, Oscar
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736836/
https://ncbi.nlm.nih.gov/pubmed/28815754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13400
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