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Influence of covariate distribution on the predictive performance of pharmacokinetic models in paediatric research

AIMS: The accuracy of model-based predictions often reported in paediatric research has not been thoroughly characterized. The aim of this exercise is therefore to evaluate the role of covariate distributions when a pharmacokinetic model is used for simulation purposes. METHODS: Plasma concentration...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Piana, Chiara, Danhof, Meindert, Della Pasqua, Oscar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Science Inc 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168389/
https://ncbi.nlm.nih.gov/pubmed/24433411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12322
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