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Influence of covariate distribution on the predictive performance of pharmacokinetic models in paediatric research
AIMS: The accuracy of model-based predictions often reported in paediatric research has not been thoroughly characterized. The aim of this exercise is therefore to evaluate the role of covariate distributions when a pharmacokinetic model is used for simulation purposes. METHODS: Plasma concentration...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Science Inc
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4168389/ https://ncbi.nlm.nih.gov/pubmed/24433411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12322 |
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