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Covariate effects and population pharmacokinetics of lamivudine in HIV-infected children

AIM: Lamivudine is used as first line therapy in HIV-infected children. Yet, like many other paediatric drugs, its dose rationale has been based on limited clinical data, without thorough understanding of the effects of growth on drug disposition. Here we use lamivudine to show how a comprehensive p...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Piana, Chiara, Zhao, Wei, Adkison, Kimberly, Burger, David, Jacqz-Aigrain, Evelyne, Danhof, Meindert, Della Pasqua, Oscar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Publishing Ltd 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004406/
https://ncbi.nlm.nih.gov/pubmed/24118070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12247
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