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Population pharmacokinetics of deferiprone in healthy subjects

AIMS: To characterize the pharmacokinetics of deferiprone in healthy subjects using a model-based approach and to assess the effect of demographic and physiological factors on drug exposure. METHODS: Data from 55 adult healthy subjects receiving deferiprone (solution 100 mg ml(−1)) were used for mod...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Br J Clin Pharmacol
Hauptverfasser: Bellanti, Francesco, Danhof, Meindert, Della Pasqua, Oscar
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256628/
https://ncbi.nlm.nih.gov/pubmed/25052529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12473
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