Reduced Retinoblastoma Protein Expression Is Associated with Decreased Patient Survival in Medullary Thyroid Cancer

Background: The retinoblastoma (RB) transcriptional corepressor 1 protein functions to slow cell-cycle progression. Inactivation of RB by reduced expression and/or hyperphosphorylation allow for enhanced progression through the cell cycle. Murine models develop medullary thyroid carcinoma (MTC) afte...

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Detalhes bibliográficos
Publicado no:Thyroid
Main Authors: Valenciaga, Anisley, Grubbs, Elizabeth G., Porter, Kyle, Wakely, Paul E., Williams, Michelle D., Cote, Gilbert J., Vasko, Vasyl V., Saji, Motoyasu, Ringel, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Thyroid Cancer and Nodules
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734142/
https://ncbi.nlm.nih.gov/pubmed/29105562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2017.0113
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