Sorafenib and Mek inhibition is synergistic in medullary thyroid carcinoma in vitro

Clinical trials using kinase inhibitors have demonstrated transient partial responses and disease control in patients with progressive medullary thyroid cancer (MTC). The goal of this study was to identify potential combinatorial strategies to improve on these results using sorafenib, a multikinase...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Koh, Yoon Woo, Shah, Manisha H, Agarwal, Kitty, McCarty, Samantha K, Koo, Bon Seok, Brendel, Victoria J, Wang, Chaojie, Porter, Kyle, Jarjoura, David, Saji, Motoyasu, Ringel, Matthew D
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717592/
https://ncbi.nlm.nih.gov/pubmed/22109971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-11-0155
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