Sorafenib and Mek inhibition is synergistic in medullary thyroid carcinoma in vitro

Clinical trials using kinase inhibitors have demonstrated transient partial responses and disease control in patients with progressive medullary thyroid cancer (MTC). The goal of this study was to identify potential combinatorial strategies to improve on these results using sorafenib, a multikinase...

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Bibliografiske detaljer
Main Authors: Koh, Yoon Woo, Shah, Manisha H, Agarwal, Kitty, McCarty, Samantha K, Koo, Bon Seok, Brendel, Victoria J, Wang, Chaojie, Porter, Kyle, Jarjoura, David, Saji, Motoyasu, Ringel, Matthew D
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717592/
https://ncbi.nlm.nih.gov/pubmed/22109971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-11-0155
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