Transcriptional targeting of oncogene addiction in medullary thyroid cancer

Metastatic medullary thyroid cancer (MTC) is incurable and FDA-approved kinase inhibitors that include oncogenic RET as a target do not result in complete responses. Association studies of human MTCs and murine models suggest that the CDK/RB pathway may be an alternative target. The objective of thi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Valenciaga, Anisley, Saji, Motoyasu, Yu, Lianbo, Zhang, Xiaoli, Bumrah, Ceimoani, Yilmaz, Ayse S., Knippler, Christina M., Miles, Wayne, Giordano, Thomas J., Cote, Gilbert J., Ringel, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141185/
https://ncbi.nlm.nih.gov/pubmed/30135308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122225
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados