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Medullary Thyroid Carcinoma Cell Lines Contain a Self-Renewing CD133(+) Population that Is Dependent on Ret Proto-Oncogene Activity

Context: Medullary thyroid carcinoma (MTC) is a cancer of the parafollicular C cells commonly caused by an inherited or acquired RET proto-oncogene mutation. Therapeutic resistance and recurrence of the disease imply the presence of cancer stem cells in MTC. Objective: In this study, we sought to id...

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Bibliografiset tiedot
Päätekijät: Zhu, Wen, Hai, Tao, Ye, Lei, Cote, Gilbert J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Endocrine Society 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805480/
https://ncbi.nlm.nih.gov/pubmed/19897677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2009-1485
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