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Medullary Thyroid Carcinoma Cell Lines Contain a Self-Renewing CD133(+) Population that Is Dependent on Ret Proto-Oncogene Activity
Context: Medullary thyroid carcinoma (MTC) is a cancer of the parafollicular C cells commonly caused by an inherited or acquired RET proto-oncogene mutation. Therapeutic resistance and recurrence of the disease imply the presence of cancer stem cells in MTC. Objective: In this study, we sought to id...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Endocrine Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2805480/ https://ncbi.nlm.nih.gov/pubmed/19897677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2009-1485 |
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