Role of CDKN2C Copy Number in Sporadic Medullary Thyroid Carcinoma

Background: The cyclin-dependent-kinase inhibitors (CDKN)/retinoblastoma (RB1) pathway has been implicated as having a role in medullary thyroid carcinoma (MTC) tumorigenesis. CDKN2C loss has been associated with RET-mediated MTC in humans but with minimal phenotypic correlation provided. The object...

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Detalhes bibliográficos
Publicado no:Thyroid
Main Authors: Grubbs, Elizabeth G., Williams, Michelle D., Scheet, Paul, Vattathil, Selina, Perrier, Nancy D., Lee, Jeffrey E., Gagel, Robert F., Hai, Tao, Feng, Lei, Cabanillas, Maria E., Cote, Gilbert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Thyroid Cancer and Nodules
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6453497/
https://ncbi.nlm.nih.gov/pubmed/27610696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2016.0224
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