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A cellular threshold for active ERK1/2 levels determines Raf/MEK/ERK-mediated growth arrest versus death responses
In addition to its conventional role for cell proliferation and survival, the Raf/MEK/Extracellular signal-regulated kinase (ERK) pathway can also induce growth arrest and death responses, if aberrantly activated. Here, we determined a molecular basis of ERK1/2 signaling that underlies these growth...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cell Signal |
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| Κύριοι συγγραφείς: | , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5732048/ https://ncbi.nlm.nih.gov/pubmed/28986121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2017.10.001 |
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