Raf/MEK/ERK can regulate cellular levels of LC3B and SQSTM1/p62 at expression levels

While cellular LC3B and SQSTM1 levels serve as key autophagy markers, their regulation by different signaling pathways requires better understanding. Here, we report the mechanisms by which the Raf/MEK/ERK pathway regulates cellular LC3B and SQSTM1 levels. In different cell types, δRaf-1:ER- or B-Ra...

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Main Authors: Kim, Jin-Hwan, Hong, Seung-Keun, Wu, Pui-Kei, Richards, Alexsia L, Jackson, William T, Park, Jong-In
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164593/
https://ncbi.nlm.nih.gov/pubmed/25128814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2014.08.001
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